Scientists say house cats could help unlock better cancer treatments for humans

Reported by ScienceDaily · September 27 at 4:01 AM · Summary by Pawdeck

Researchers analyzed tumor samples from almost 500 domestic cats in five countries, mapping the genetic changes behind feline cancers on a scale not attempted before. Many of the driver genes found in cat tumors were also seen in human and dog cancers, and certain chemotherapy drugs worked better against cat mammary tumors carrying a mutated FBXW7 gene, a finding so far observed only in tissue samples.

Background

Cancer driver genes are genes whose damage lets cells grow and divide without control. Comparing naturally occurring tumors across species is a long-standing way for researchers to find shared biology, and lab results on tissue usually need further testing in living animals before any treatment changes.

Why it matters

Cancer is a leading cause of illness and death in cats, and better genetic understanding could eventually shape how veterinarians choose treatments for them.

What you can do

If your cat has been diagnosed with a tumor, ask your veterinarian whether genetic testing or a referral to a veterinary oncologist could be useful for your cat's specific case.

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Written by Pawdeck from the report by ScienceDaily. Background is general information, not advice about your pet; if you are worried, call your vet.